计算力学与工程系列讲座报告第二十二讲通知(2023-36)

报告题目：Computational Modeling of Vesicles in Interaction with Fluid Field and Electric Field

报告时间：2023年8月12日（周六）13:00（北京时间）

报告地点：河海大学（西康路校区）闻天馆209

报  告  人：Timon Rabczuk 教授，德国魏玛-包豪斯大学

主办单位：云顶yd2222咋登录不了固体力学研究所

欢迎广大师生参加！

报告摘要：

The use of electric fields as an external stimulus has been shown to be an effective technique for engineering vesicle behavior in a wide range of biotechnological applications. Electroporation has been successfully utilized for introducing genes or drugs into cells and cancer treatments. As a powerful cell manipulation method, electric fields have been used in tissue ablation, wound healing, and electroformation and electrofusion of giant vesicles. These important applications have motivated theoretical and computational studies on electrohydrodynamics of vesicles in order to gain a better understanding of the variety of membrane responses under the influence of electric and flow fields. In this talk, the work devoted to developing a robust computational framework using isogeometric analysis and the phase-field method to model the morphological evolution of single- and multi-phase biomembranes will be presented. We developed a three-dimensional isogeometric analysis formulation for the phase-field constrained optimization problem of morphological evolution of vesicles in electrical fields. The effect of the flexoelectricity and the conductivity ratio of the electrolyte on vesicle equilibrium shape were studied through several 3D numerical examples. We captured sphere-oblate and sphere-prolate shape transitions under varying conductivity ratio.

报告人简介：

Timon Rabczuk教授，德国国立包豪斯-魏玛大学计算力学讲席教授 (Chair Professor)，欧洲科学与艺术学院院士、欧洲科学院院士、德国洪堡基金会费-吕楠奖获得者，入选“工程”与“计算科学”双领域科睿唯安ISI全球高被引学者。Rabczuk教授主要从事计算力学与先进材料计算设计方向的研究，十多年来Rabczuk 教授课题组培养了30多名来自中国的博士生与博后，先后8人获得了国家级人才计划或洪堡学者等国际人才奖励。